Forum LABO Paris 2027

PDG

Prof. Davy GUILLARME

Université de Lyon / Université de Genève

Docteur en chimie analytique et Professeur associé

Description

Davy Guillarme, Ph.D. in analytical chemistry from the University of Lyon, currently serves as an associate professor at the University of Geneva in Switzerland. With almost 400 published journal articles in pharmaceutical analysis and h-index of 86, his expertise spans various techniques, including HPLC/UHPLC, HILIC, LC−MS, SFC, SFC-MS, multidimensional LC, and analysis of biopharmaceuticals. He is an editor of the Journal of Chromatography A and serves on the editorial advisory board of prestigious journals like Trends in Analytical Chemistry, Journal of Chromatography B, Journal of Separation Science,... Davy Guillarme has been honored with the LC-GC Emerging Leader Award in Chromatography (2013), Jubilee Medal from the Chromatographic Society (2018), International Award of the Belgian Society of Pharmaceutical Sciences (2022), Csaba Horvath memorial award (2025), J.F.K. Huber lecture award (2026). He has also been listed among the world's most influential analytical scientists by "Analytical Scientist" magazine in multiple years.

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Agora
Mar 24, 2027
12:00 PM12:45 PM
Biotechnology, science and healthcare of tomorrow

New approaches to biopharmaceutical analysis - AFSEP

Speakers:
Prof. Davy GUILLARMEUniversité de Lyon / Université de GenèveDocteur en chimie analytique et Professeur associé
Description
Biopharmaceutical drugs are playing an increasingly important role in the pharmaceutical industry. This evolution is accompanied by a wide diversity of molecules, including monoclonal antibodies and their derivatives, oligonucleotides, messenger RNA, as well as cell and gene therapies. Their size, structure, and complexity make their analysis particularly challenging. Yet in-depth characterization is essential to verify their identity, purity, and integrity, detect variants and impurities, and better understand the links between their properties and their biological activity. This presentation will first cover the main families of biopharmaceuticals and the analytical challenges they raise. It will then show how different chromatographic approaches, with or without mass spectrometry, can contribute to their characterization. Examples will illustrate the complementarity of chromatographic modes, the development of rapid analyses, coupling with MS, and method automation. Finally, the biopharmaceuticals of tomorrow are expected to become even more complex, particularly with the rise of conjugated molecules combining several types of compounds. This evolution will require the continued development of adapted analytical strategies capable of providing ever more comprehensive and reliable information.
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