Forum LABO Paris 2027

Hemarina – a human, scientific and entrepreneurial adventure

Mar 23, 2027 — 03:00 pm - 3:45 PM
Salle Marie Curie

Biotechnology, science and healthcare of tomorrow
Hemarina – a human, scientific and entrepreneurial adventure

Description

Oxygen is essential to life, and hemoglobin is the molecule responsible for transporting almost all of the oxygen present in the circulatory system of most living species. During this conference, our speaker will retrace the story of the discovery of a natural extracellular hemoglobin called M101, derived from a marine organism, Arenicola marina, and its applications in medicine. This non-allergenic and non-immunogenic molecule carries 40 times more oxygen than HbA and is 250 times smaller than a red blood cell. Its intrinsic properties make it a broad-spectrum therapeutic tool for ensuring effective tissue oxygenation in various clinical situations where ischemia and/or anemia are the triggering factors. The applications of the M101 molecule are almost limitless, as it can potentially act wherever oxygen is needed: in composite tissue transplants (organs, skin, face, limbs, etc.), during vaso-occlusive crises in patients with sickle cell disease, in cases of myocardial infarction, cerebral ischemia, in oncology (radiotherapy, CAR-T cells for hypoxic tumors), in the development of oxygenating dressings for hypoxic wounds, and in the treatment of periodontal diseases. This presentation will provide an overview of the development of the M101 molecule and its various therapeutic applications.

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